ProPac 離子交換色譜柱
Strong and weak cation-exchange columns for the high-resolution separation of proteins and MAbs
ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.
• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-efficiency separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g.,deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development
The ProPac SCX-10 is a strong cation exchange column with sulfonate functional groups. The ProPac WCX-10 has a carboxylate functional group. Both are based on 10 μm nonporous,polymeric beads and coated with a proprietary hydrophilic layer.
All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to column and lot-to-lot reproducibility. Dionex also offers ProPac columns as a lot select package: either three columns from one lot or three columns from three different lots, to assist quality control scientists in method validation.
訂貨信息:
SCX Analytical Columns
ProPac SCX-10 Analytical Column (4 × 250 mm).......................................... 054995
ProPac SCX-10 Analytical Column (2 × 250 mm).......................................... 063456
ProPac SCX-10 Semipreparative Column (9 × 250 mm)................................. 063700
ProPac SCX-10 Semipreparative Column (22 × 250 mm)................................SP5522
ProPac SCX-10 Lot Select Column Set (4 × 250 mm) (1 lot of resin)...............SP5727
ProPac SCX-10 Lot Select Column Set (4 × 250 mm) (3 lots of resin).............SP5728
SCX Guard Columns
ProPac SCX-10G Guard Column (4 × 50 mm).............................................. 054996
ProPac SCX-10G Guard Column (2 × 50 mm).............................................. 063462
WCX Analytical Columns
ProPac WCX-10 Analytical Column (2 × 250 mm)........................................ 063472
ProPac WCX-10 Analytical Column (4 × 100 mm).........................................SP5829
ProPac WCX-10 Analytical Column (4 × 250 mm)........................................ 054993
ProPac WCX-10 Lot Select 3 Column Set (4 × 250 mm) (1 lot of resin)...........SP5512
ProPac WCX-10 Lot Select 3 Column Set (4 × 250 mm) (3 lots of resin)..........SP5513
ProPac WCX-10 Semipreparative Column (9 × 250 mm)................................ 063474
ProPac WCX-10 Semipreparative Column (22 × 250 mm)...............................SP5482
WCX Guard Columns
ProPac WCX-10G Guard Column (2 × 50 mm).............................................. 063480
ProPac WCX-10G Guard Column (4 × 50 mm).............................................. 054994
應用譜圖:



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